YRP01177-01
[Polyclonal Antibody]
N-cadherin Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC IF |
| Immunogen Range: |
KLH conjugated synthetic peptide derived from human N-cadherin |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
1000 |
| Swiss Prot: |
P19022 |
| Synonyms: |
CDHN, NCAD, CD325, CDw325, Cadherin-2, Neural cadherin, N-cadherin, CDH2 |
| Purification: |
Purified by Protein A. |
| Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). |
| Caculated MW: |
/ |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!