
| Species: | Rabbit |
| Applications: | WB IF ICC |
| Immunogen Range: | A synthetic peptide |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 4158 |
| Swiss Prot: | Q01718 |
| Synonyms: | ACTH receptor, ACTH-R, ACTHR, adrenocorticotropic hormone receptor, adrenocorticotropin receptor, MC2-R, melanocortin-2 receptor |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. |
| Caculated MW: | 34 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:1000 IF 1:100-1:500 ICC 1:100-1:500 |
| Reacitivity: | Human, Mouse |