ARP22914-61
[Polyclonal Antibody]
KLRK1 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
22914 |
| Swiss Prot: |
P26718 |
| Synonyms: |
NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NK cell receptor D, Killer cell lectin-like receptor subfamily K member 1, CD314, KLRK1, D12S2489E, NKG2D |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. [provided by RefSeq |
| Caculated MW: |
25 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:1000
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!