ARP699-62
[Polyclonal Antibody]
BUB1 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
699 |
Swiss Prot: |
O43683 |
Synonyms: |
BUB1A, BUB1L, hBUB1, MBUB1, Mitotic checkpoint BUB1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. |
Caculated MW: |
120 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:1000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!