ARP8428-61
[Polyclonal Antibody]
STK24 Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
8428 |
Swiss Prot: |
Q9Y6E0 |
Synonyms: |
EC 2.7.11.1, STE20-like kinase MST3, MST-3, Mammalian STE20-like protein kinase 3 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM |
Caculated MW: |
50 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:1000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!