ARP3736-61
[Polyclonal Antibody]
KCNA1 Rabbit Polyclonal Antibody
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| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
3736 |
| Swiss Prot: |
Q09470 |
| Synonyms: |
HBK1, HUKI, KCNA1, potassium channel Kv1.1, potassium voltage-gated channel subfamily A member 1 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). |
| Caculated MW: |
57 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:1000
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!