ARP8504-61
[Polyclonal Antibody]
PEX3 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
8504 |
Swiss Prot: |
P56589 |
Synonyms: |
peroxin-3, peroxisomal assembly PEX3, peroxisomal biogenesis factor 3, PEX3 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq |
Caculated MW: |
42 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:1000
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!