ARP5511-61
[Polyclonal Antibody]
PPP1R8 Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
5511 |
Swiss Prot: |
Q12972 |
Synonyms: |
activator of RNA decay, ARD-1, ARD1, EC 3.1.4.-, NIPP1, nuclear inhibitor of protein phosphatase-1, PP1R8, PPP1R8, PPR8, protein phosphatase 1, regulatory inhibitor subunit 8 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008] |
Caculated MW: |
40 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:1000
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!