ARP80184-61
[Polyclonal Antibody]
CEP290 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
80184 |
| Swiss Prot: |
O15078 |
| Synonyms: |
CE290, centrosomal protein Cep290, CTCL tumor antigen se2-2, JBTS5, JBTS6, Joubert syndrome 5, LCA10, nephrocystin-6, NPHP6, SLSN6 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq |
| Caculated MW: |
290 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:1000
|
| Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!