ARP1369-61
[Polyclonal Antibody]
CPN1 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
1369 |
| Swiss Prot: |
P15169 |
| Synonyms: |
anaphylatoxin inactivator, arginine carboxypeptidase, carboxypeptidase N 1, carboxypeptidase N catalytic, carboxypeptidase N polypeptide 1 50 kD, carboxypeptidase N small subunit, CBPN, CPN, EC 3.4.17.3, kininase-1, lysine carboxypeptidase, plasma carboxy |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq |
| Caculated MW: |
52 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:1000
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!