ARP22901-61
[Polyclonal Antibody]
ARSG Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB IHC |
| Immunogen Range: |
A synthetic peptide |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
22901 |
| Swiss Prot: |
Q96EG1 |
| Synonyms: |
Arylsulfatase G, EC 3.1.6.-, ASG |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors. [provided by RefSeq |
| Caculated MW: |
65 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:1000 IHC 1:50-1:200
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!