ARP63941-61 [Polyclonal Antibody]
NECAB3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF ICC
Immunogen Range:   A synthetic peptide
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   63941
Swiss Prot:   Q96P71
Synonyms:   AB2BP, amyloid beta A4 protein-binding family A member 2-binding, APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, N-terminal EF-hand calcium binding 3, NECA3, NECAB 3, Nek2-interacting 1, neuronal calcium-binding 3, NIP1, STIP3, SYTIP2, X11L-binding 51, XB51
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Caculated MW:   44 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information