ARP6182-61
[Polyclonal Antibody]
MRPL12 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
6182 |
Swiss Prot: |
P52815 |
Synonyms: |
39S ribosomal protein L12, mitochondrial, 5c5-2, L12mt, MRP-L12, RM12, RPML12 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq |
Caculated MW: |
21 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:1000
|
Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!