ARPF074-65 [Polyclonal Antibody]
Cytochrome P450 1A1/2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1543/1544
Swiss Prot:   P04798/P05177
Synonyms:   AHH, AHRR, CP11, CYP1, CYPIA1, EC 1.14.14.1, P1-450, P450 form 6, P450-C, P450-P1, P450DX, aryl hydrocarbon hydroxylase, cytochrome P1-450, dioxin-inducible, cytochrome P450 1A1, cytochrome P450 1A1 variant, cytochrome P450, family 1, subfamily A, polypep
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]
Caculated MW:   58 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information