ARP8539-61
[Polyclonal Antibody]
API-5 Rabbit Polyclonal Antibody
www.yhsbio.com
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB IHC |
| Immunogen Range: |
A synthetic peptide |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
8539 |
| Swiss Prot: |
Q9BZZ5 |
| Synonyms: |
AAC-11, API-5, API5-like 1, API5L1, FIF, XAGL protein, apoptosis inhibitor 5, fibroblast growth factor 2-interacting factor, fibroblast growth factor 2-interacting factor 2, migration-inducing protein MIG8 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
| Caculated MW: |
58 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:1000 IHC 1:50-1:200
|
| Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!