ARP9451-61
[Polyclonal Antibody]
E2AK3 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IF ICC |
| Immunogen Range: | A synthetic peptide |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 9451 |
| Swiss Prot: | Q9NZJ5 |
| Synonyms: | E2AK3, EC 2.7.11.1, EIF2AK3, Eukaryotic translation initiation factor 2-alpha kinase 3 precursor, HsPEK, PEK, PERK, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, kinase PERK |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
| Caculated MW: | 125 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:1000 IF 1:100-1:500 ICC 1:100-1:500 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
