ARP8569-62
[Polyclonal Antibody]
MKNK1 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | A synthetic peptide |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 8569 |
| Swiss Prot: | Q9BUB5 |
| Synonyms: | MAP kinase-interacting serine/threonine-protein kinase 1, EC 2.7.11.1, MAP kinase signal-integrating kinase 1, Mnk1, MKNK1, MNK1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | Mnk1 a CAM kinase of the MAPKKAPK family that can regulate translation. Following activation by MAP kinases, Mnk1 phosphorylates eIF4E at Ser209, increasing its affinity for the 7-methylguanosine-containing mRNA cap. Two MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for its kinase activity. Three alternatively spliced human isoforms have been described. |
| Caculated MW: | 51 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:1000 |
| Reacitivity: | Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
