ARP6834-62
[Polyclonal Antibody]
SURF1 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
6834 |
| Swiss Prot: |
Q15526 |
| Synonyms: |
Surfeit locus protein 1, SURF1, SURF-1 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. |
| Caculated MW: |
30 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:1000
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!