
| Species: | Rabbit |
| Applications: | IHC IF ICC |
| Immunogen Range: | A synthetic peptide |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 7019 |
| Swiss Prot: | Q00059 |
| Synonyms: | RTEF1, TCF13L1, TEA domain family member 4, TEAD-4, TEAD4, TEF3, transcription factor RTEF-1, transcriptional enhancer factor TEF-3 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells. |
| Caculated MW: | 29 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
| Reacitivity: | Human |