ARP94-61 [Polyclonal Antibody]
ACVRL1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF ICC
Immunogen Range:   A synthetic peptide derived from human ACVRL1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   94
Swiss Prot:   P37023
Synonyms:   HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I, ACVRLK1
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Caculated MW:   56 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information