ARP9227-62 [Polyclonal Antibody]
LRAT Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF ICC
Immunogen Range:   A synthetic peptide
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   9227
Swiss Prot:   O95237
Synonyms:   Lecithin retinol acyltransferase, EC 2.3.1.135, Phosphatidylcholine--retinol O-acyltransferase, LRAT
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   LRAT Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments. Belongs to the H-rev107 family. LRAT activity is up-regulated by dietary vitamin A.
Caculated MW:   27 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information