Species: | Rabbit |
Applications: | WB IHC IF ICC |
Immunogen Range: | A synthetic peptide |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 8742 |
Swiss Prot: | O43508 |
Synonyms: | Tumor necrosis factor ligand superfamily member 12, TNF-related weak inducer of apoptosis, TWEAK, APO3 ligand, Tumor necrosis factor ligand superfamily member 12, membrane form, Tumor necrosis factor ligand superfamily member 12, secreted form, TNFSF12 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | TNFSF12 Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Belongs to the tumor necrosis factor family. Homotrimer (Potential). Interacts with the angiogenic factor AGGF1/VG5Q |
Caculated MW: | 27 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:1000 IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse |