Species: | Rabbit |
Applications: | WB IF ICC |
Immunogen Range: | A synthetic peptide |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 10403 |
Swiss Prot: | O14777 |
Synonyms: | HEC1, HEC, Highly expressed in cancer, rich in leucine heptad repeats, KNTC2, NDC80, Retinoblastoma-associated protein HEC, TID3, kinetochore associated 2 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. |
Caculated MW: | 73 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:1000 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse |