AMM1973-61
[Monoclonal Antibody]
eIF4A1 Mouse Monoclonal Antibody
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DATASHEET
| Species: |
Mouse |
| Applications: |
WB |
| Immunogen Range: |
Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG1 |
| GENE ID: |
1973 |
| Swiss Prot: |
P60842 |
| Synonyms: |
DDX2, eIF 4A I, Eukaryotic initiation factor 4A-1, ATP-dependent RNA helicase eIF4A-1,DDX2A |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA – this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression. |
| Caculated MW: |
48 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:1000-1:3000
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!