AMM6997-61 [Monoclonal Antibody]
TDGF1 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA
Immunogen Range:   A purified recombinant fragment of human TDGF1 expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   6997
Swiss Prot:   P13385
Synonyms:   CR, CRGF, CRIPTO, TDGF1
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.
Caculated MW:   21 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information