AMM332-62 [Monoclonal Antibody]
BIRC5 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IHC ELISA ICC FC
Immunogen Range:   A purified recombinant fragment of human BIRC5 expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   332
Swiss Prot:   O15392
Synonyms:   API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, BIRC5, Baculoviral IAP repeat-containing protein 5, IAP4, TIAP
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   survivin is an apoptosis inhibitor that is expressed during the G2/M phase of the cell cycle. Associates with the microtubules of the mitotic spindle and any disruption results in the loss of apoptosis activity. May play a role in neoplasia. Inhibitor of caspase-3 and caspase-7. Two splice variant isoforms have been described.
Caculated MW:   16 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information