AMM55486-61 [Monoclonal Antibody]
PARL Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA
Immunogen Range:   A purified recombinant fragment of human PARL expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   55486
Swiss Prot:   Q9H300
Synonyms:   PSARL, PSARL1, RHBDS1
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Caculated MW:   42 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information