AMM6929-61
[Monoclonal Antibody]
TCF3 Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | WB ELISA FC |
| Immunogen Range: | A purified recombinant fragment of human TCF3 expressed in E. Coli |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG1 |
| GENE ID: | 6929 |
| Swiss Prot: | P15923 |
| Synonyms: | E12, Immunoglobulin enhancer binding factor E12/E47, Immunoglobulin transcription factor-1, ITF1, Kappa-E2-binding factor, TCF-3, TCF3, TFE2, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), Transcription factor E2-alpha, Tran |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described. |
| Caculated MW: | 68 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 FC 1:200-1:400 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
