AMM4155-61
[Monoclonal Antibody]
MBP Mouse Monoclonal Antibody
www.yhsbio.com
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support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | WB IHC ELISA ICC FC |
| Immunogen Range: | A purified recombinant fragment of human MBP expressed in E. Coli |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG1 |
| GENE ID: | 4155 |
| Swiss Prot: | P02686 |
| Synonyms: | Myelin A1 protein, myelin basic protein, Myelin membrane encephalitogenic protein |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | The classic group of MBP isoforms (isoforms 4-14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non- classic group of MBP isoforms (isoforms 1-3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T- cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function. |
| Caculated MW: | 33 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000 ICC 1:200-1:1000 FC 1:200-1:400 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
