AMM23406-61
[Monoclonal Antibody]
COTL1 Mouse Monoclonal Antibody
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| Species: |
Mouse |
| Applications: |
WB IHC ELISA |
| Immunogen Range: |
A purified recombinant fragment of human COTL1 expressed in E. Coli |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG1 |
| GENE ID: |
23406 |
| Swiss Prot: |
Q14019 |
| Synonyms: |
CLP |
| Purification: |
Affinity chromatography |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. |
| Caculated MW: |
16 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!