AMM925-61 [Monoclonal Antibody]
CD8 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   ELISA FC
Immunogen Range:   A purified recombinant fragment of human CD8 expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   925
Swiss Prot:   P01732
Synonyms:   CD8, MAL, p32, Leu2, CD8A
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine- protein kinase p56lck.
Caculated MW:   25 kDa
Observed MW:   Refer to Figures
Applications:   FC 1:200-1:400
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information