AMM1029-61 [Monoclonal Antibody]
CDKN2A Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IHC ELISA
Immunogen Range:   A purified recombinant fragment of human CDKN2A expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1 Kappa
GENE ID:   1029
Swiss Prot:   P42771
Synonyms:   CDKN4, KIP1, MEN1B, MEN4, P27KIP1
Purification:   Affinity purification
Storage:   Store at 4°C in PBS, pH 7.4 (protein base, sodium azide).
Background:   This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq
Caculated MW:   16 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:200-1:1000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information