Species: | Mouse |
Applications: | WB IHC ELISA ICC FC |
Immunogen Range: | A purified recombinant fragment of human MAPK3 expressed in E. Coli |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 |
GENE ID: | 5594 |
Swiss Prot: | P27361/P28482 |
Synonyms: | EC 2.7.11.24, ERK-1, ERK1, ERT2, Extracellular signal- regulated kinase 1, Insulin-stimulated MAP2 kinase, kinase ERK1, MAP kinase 1, MAPK 1, MAPK3, Microtubule- associated protein-2 kinase, Mitogen-activated protein kinase 3, MK03, MNK1, p44-ERK1, P44-ER |
Purification: | Affinity chromatography |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | p42 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Activated by a wide variety of extracellular signals including growth and neurotrophic factors, cytokines, hormones and neurotransmitters. Activation of MAP kinases occurs through phosphorylation of threonine and tyrosine residues at the sequence T*EY* by a single upstream MAP kinase kinase, MEK. |
Caculated MW: | 44 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000 ICC 1:200-1:1000 FC 1:200-1:400 |
Reacitivity: | Human, Monkey, Mouse, Rat |