AMM4314-61 [Monoclonal Antibody]
MMP3 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA FC
Immunogen Range:   A purified recombinant fragment of human MMP3 expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   4314
Swiss Prot:   P08254
Synonyms:   EC 3.4.24.17Matrix metalloproteinase-3MMP3Transin-1SL-1
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Caculated MW:   54 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
FC 1:200-1:400
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information