AMM4041-61 [Monoclonal Antibody]
LRP5 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA FC
Immunogen Range:   A purified recombinant fragment of human LRP5 expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   4041
Swiss Prot:   O75197
Synonyms:   HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, OPTA1, VBCH2
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Caculated MW:   179 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
FC 1:200-1:400
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information