AMM6271-61
[Monoclonal Antibody]
S100A1 Mouse Monoclonal Antibody
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| Species: |
Mouse |
| Applications: |
WB IHC ELISA |
| Immunogen Range: |
A purified recombinant fragment of human S100A1 expressed in E. Coli |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG1 |
| GENE ID: |
6271 |
| Swiss Prot: |
P23297 |
| Synonyms: |
S100, S100A, S100-alpha, S100A1 |
| Purification: |
Affinity chromatography |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
S100 calcium binding protein A1 (S100-alpha/ S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. |
| Caculated MW: |
11 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!