
| Species: | Mouse |
| Applications: | WB IHC ELISA ICC |
| Immunogen Range: | A purified recombinant fragment of human FMR1 expressed in E. Coli |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG1 |
| GENE ID: | 2332 |
| Swiss Prot: | Q06787 |
| Synonyms: | POF, FMRP, POF1, FRAXA |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. |
| Caculated MW: | 71 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000 ICC 1:200-1:1000 |
| Reacitivity: | Human |