AMM59349-61
[Monoclonal Antibody]
KLHL12 Mouse Monoclonal Antibody
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DATASHEET
| Species: |
Mouse |
| Applications: |
WB ELISA |
| Immunogen Range: |
A purified recombinant fragment of human KLHL12 expressed in E. Coli |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG1 |
| GENE ID: |
59349 |
| Swiss Prot: |
Q53G59 |
| Synonyms: |
DKIR, C3IP1, FLJ27152, KLHL12 |
| Purification: |
Affinity chromatography |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland. |
| Caculated MW: |
63 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!