AMM10516-62
[Monoclonal Antibody]
FBLN5 Mouse Monoclonal Antibody
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Species: |
Mouse |
Applications: |
WB IHC ELISA |
Immunogen Range: |
A purified recombinant fragment of human FBLN5 expressed in E. Coli |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 |
GENE ID: |
10516 |
Swiss Prot: |
Q9UBX5 |
Synonyms: |
EVEC, UP50, ARMD3, DANCE |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. |
Caculated MW: |
50 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!