AMM9451-61
[Monoclonal Antibody]
EIF2AK3 Mouse Monoclonal Antibody
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DATASHEET
Species: |
Mouse |
Applications: |
WB ELISA |
Immunogen Range: |
A purified recombinant fragment of human EIF2AK3 expressed in E. Coli |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 |
GENE ID: |
9451 |
Swiss Prot: |
Q9NZJ5 |
Synonyms: |
EC 2.7.11.1PRKR-like endoplasmic reticulum kinasePancreatic eIF2-alpha kinaseHsPEK |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Caculated MW: |
125 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!