AMM10313-61 [Monoclonal Antibody]
RTN3 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   ELISA ICC
Immunogen Range:   A purified recombinant fragment of human RTN3 expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   10313
Swiss Prot:   O95197
Synonyms:   HAP, ASYIP, NSPL2, NSPLII, RTN3-A1
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Caculated MW:   113 kDa
Observed MW:   Refer to Figures
Applications:   ICC 1:200-1:1000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information