AMM637-61 [Monoclonal Antibody]
BID Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IHC ELISA ICC FC
Immunogen Range:   A purified recombinant fragment of human BID expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   637
Swiss Prot:   P55957
Synonyms:   BH3 interacting domain death agonist
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Caculated MW:   22 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information