AMM2046-61
[Monoclonal Antibody]
EphA8 Mouse Monoclonal Antibody
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Species: |
Mouse |
Applications: |
WB ELISA |
Immunogen Range: |
A purified recombinant fragment of human EphA8 expressed in E. Coli |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 |
GENE ID: |
2046 |
Swiss Prot: |
P29322 |
Synonyms: |
EC 2.7.10.1, EEK, EPH-and ELK-related kinase, Ephrin type-A receptor 8 precursor, HEK3, KIAA1459, Tyrosine-protein kinase receptor EEK, kinase EphA8 |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. |
Caculated MW: |
111 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!