AMM6855-61
[Monoclonal Antibody]
SYP Mouse Monoclonal Antibody
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Species: |
Mouse |
Applications: |
WB IHC ELISA |
Immunogen Range: |
A purified recombinant fragment of human SYP expressed in E. Coli |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 |
GENE ID: |
6855 |
Swiss Prot: |
P08247 |
Synonyms: |
MRXSYP, SYP |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex. |
Caculated MW: |
34 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000
|
Reacitivity: |
Hunam, Rat |
For research use only. Not intended for diagnostic or therapeutic use!