AMM4793-61
[Monoclonal Antibody]
NFKBIB Mouse Monoclonal Antibody
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DATASHEET
| Species: |
Mouse |
| Applications: |
WB ELISA |
| Immunogen Range: |
A purified recombinant fragment of human NFKBIB expressed in E. Coli |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG1 |
| GENE ID: |
4793 |
| Swiss Prot: |
Q15653 |
| Synonyms: |
IKBB, TRIP9, NFKBIBClone# 7B4 |
| Purification: |
Affinity chromatography |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined. |
| Caculated MW: |
45 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!