AMM1051-61
[Monoclonal Antibody]
CEBPB Mouse Monoclonal Antibody
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DATASHEET
Species: |
Mouse |
Applications: |
WB ELISA FC |
Immunogen Range: |
A purified recombinant fragment of human CEBPB expressed in E. Coli |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 |
GENE ID: |
1051 |
Swiss Prot: |
P17676 |
Synonyms: |
AGP/EBP, C/EBP beta, C/EBP-related protein 2, CCAAT/enhancer binding protein beta, CEBPB, CRP2, IL-6DBP, Interleukin-6- dependent binding protein, LAP, Liver-enriched transcriptional activator, Nuclear factor NF-IL6, SF-B, SFB, Silencer factor B, TCF5, Tr |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. |
Caculated MW: |
36 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 FC 1:200-1:400
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!