AMM2049-62
[Monoclonal Antibody]
EphB3 Mouse Monoclonal Antibody
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DATASHEET
Species: |
Mouse |
Applications: |
WB IHC ELISA |
Immunogen Range: |
A purified recombinant fragment of human EphB3 expressed in E. Coli |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 |
GENE ID: |
2049 |
Swiss Prot: |
P54753 |
Synonyms: |
Developmental kinase 5, EC 2.7.10.1, ETK2, Ephrin type-B receptor 3 precursor, HEK2, MDK5, SEK-4, SEK4, Tyrosine-protein kinase receptor MDK-5, kinase EphB3, tyrosine-protein kinase receptor HEK-2 |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. |
Caculated MW: |
110 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!