AMM3718-61 [Monoclonal Antibody]
JAK3 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA ICC FC
Immunogen Range:   A purified recombinant fragment of human JAK3 expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   3718
Swiss Prot:   P52333
Synonyms:   EC 2.7.10.2, JAK-3, JAK3, Janus kinase 3, L-JAK, Leukocyte janus kinase, kinase Jak3
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Caculated MW:   125 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
ICC 1:200-1:1000
FC 1:200-1:400
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information