AMM7412-61
[Monoclonal Antibody]
VCAM1 Mouse Monoclonal Antibody
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| Species: |
Mouse |
| Applications: |
WB IHC ELISA |
| Immunogen Range: |
A purified recombinant fragment of human VCAM1 expressed in E. Coli |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG1 |
| GENE ID: |
7412 |
| Swiss Prot: |
P19320 |
| Synonyms: |
CD106, MGC99561, INCAM-100, DKFZp779G2333, VCAM1 |
| Purification: |
Affinity chromatography |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells. |
| Caculated MW: |
81 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!