Species: | Mouse |
Applications: | WB ELISA ICC FC |
Immunogen Range: | A purified recombinant fragment of human COX4I1 expressed in E. Coli |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 |
GENE ID: | 1327 |
Swiss Prot: | P13073 |
Synonyms: | COX IV-1, COX4, COXIV, EC 1.9.3.1, cytochrome c oxidase polypeptide IV |
Purification: | Affinity chromatography |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. |
Caculated MW: | 19 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 ICC 1:200-1:1000 FC 1:200-1:400 |
Reacitivity: | Human, Monkey, Rat, Mouse |